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Is bipolar disorder fatal? People with bipolar disorder are at risk for an array of fatal illnesses, according to a review of 17 studies involving more than 331,000 patients. The chronic stress of bipolar illness may lead to metabolic syndrome and atherosclerosis, or to insulin resistance, which increase the risk for sudden cardiac death. Do you need medication for bipolar? Bipolar disorder requires lifelong treatment with medications, even during periods when you feel better. People who skip maintenance treatment are at high risk of a relapse of symptoms or having minor mood changes turn into full-blown mania or depression. Day treatment programs.
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